10250-27-8

Benzocaine Hydrochloride CAS 23239-88-5
Product name	Benzocaine Hcl
Application	antihypertensive
CAS No.	23239-88-5
Molecular weight	201.65
Appearance	A whitepowder
Melting Point	291-292 ºC

Procaine hydrochloride Biological Activity
Description： Procaine Hydrochloride is a local anesthetic drug of the amino ester group.Target: OthersProcaine is a local anesthetic of the ester type that has a slow onset and a short duration of action.Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM [1]. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest [2]. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale [3].
Related Catalog：
Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor
Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Research Areas >> Neurological Disease
References：
[1]. Fan, P. and F.F. Weight, Procaine impairs the function of 5-HT3 receptor-ion channel complex in rat sensory ganglion neurons. Neuropharmacology, 1994. 33(12): p. 1573-9.

[2]. Villar-Garea, A., et al., Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res, 2003. 63(16): p. 4984-9.

[3]. Adamec, R.E. and C. Stark-Adamec, The effects of procaine HCl on population cellular and evoked response activity within the limbic system of the cat. Evidence for differential excitatory action of procaine in a variety of limbic circuits. Prog Neuropsychopharmacol Biol Psychiatry, 1987. 11(4): p. 345-64.

Common name of the product:  Propanoyl chloride

Product Name: Bmk Powder

Common Name N-(tert-Butoxycarbonyl)-4-piperidone
CAS Number 79099-07-3 Density 1.1±0.1 g/cm3
Boiling Point 289.8±33.0 °C at 760 mmHg
Melting Point 73-77 °C(lit.)
Molecular Formula C10H17NO3
Molecular Weight 199.247
Flash Point 129.1±25.4 °C
Exact Mass 199.120850
PSA 46.61000
LogP 0.38
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.481
Storage condition Store at 0-5°C
Water Solubility slightly soluble

Common name of the product: tert-butyl 4-(4-fluoroanilino)piperidine-1-carboxylate

Product Name: Bmk Powder

Common Name:  PMK ethyl glycidate
CAS Number:       28578-16-7

Common Name:  PMK ethyl glycidate
CAS Number:       28578-16-7

Density 1.28g/cm3
Boiling Point 334.3ºC at 760 mmHg
Molecular Formula C10H10NaO3+
Molecular Weight 201.17400
Flash Point 136.7ºC
Exact Mass 201.05300

Product Name: Bmk Powder

Density 1.28g/cm3
Boiling Point 334.3ºC at 760 mmHg
Molecular Formula C10H10NaO3+
Molecular Weight 201.17400
Flash Point 136.7ºC
Exact Mass 201.05300

Product Name	diethyl 2-(2-phenylacetyl)propanedioate
Cas Number	20320-59-6
Molecular Weight	278.30000
Exact Mass	278.11500
PSA	69.67000
LogP	1.54060

Product Name	diethyl 2-(2-phenylacetyl)propanedioate
Cas Number	20320-59-6
Molecular Weight	278.30000
Exact Mass	278.11500
PSA	69.67000
LogP	1.54060

Common Name	1-Phenyl-2-nitropropene
CAS Number	705-60-2	Molecular Weight	163.173
Density	1.1±0.1 g/cm3	Boiling Point	263.0±9.0 °C at 760 mmHg
Molecular Formula	C9H9NO2	Melting Point	63-65ºC
MSDS	N/A	Flash Point	115.7±11.5 °C