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Anti-Aging L-Carnosine CAS 305-84-0

Carnosine (English: carnosine), the scientific name β-alanyl-L-histidine (β-alanyl-L-histidine), is a kind of two amino acids composed of β-alanine and L-histidine. Peptide. The tissues of muscles and brain contain very high concentrations of carnosine.
Carnosine was discovered by the Russian chemist Gulevich along with carnitine. Studies in the United Kingdom, South Korea, Russia and other countries have shown that carnosine has a strong antioxidant capacity and is beneficial to the human body. Carnosine has been proven to scavenge reactive oxygen radicals (ROS) and α-β unsaturated aldehydes formed by excessive oxidation of fatty acids in cell membranes during oxidative stress.
Many studies have found that N-acetylcarnosine has a good effect in the prevention and treatment of cataracts. One of the studies has shown that carnosine can improve cataracts caused by turbidity of the rat's lens caused by exposure to guanidine. Although these claims support the function of carnosine. Treatment of cataracts and other hypothetical benefits to the eye, but so far, it has not received sufficient support from the mainstream medical community. For example, the Royal Ophthalmology Department of the United Kingdom once claimed that carnosine is neither safe nor effective in the local treatment of cataracts.
In a 2002 research report, it was pointed out that carnosine can improve the relationship between children with autism and society and increase the vocabulary used by children with autism. However, the improvement claimed in the research may also come from maturity. , Placebo effect, or other factors not included in this research report.
In animal experiments, carnosine supplementation can increase the content of cortisol, which may explain the hyperkinetic symptoms sometimes caused by high-dose carnosine. However, the above study was to inject carnosine into the cerebral ventricle of chickens and cortisol The phenomenon of rising content has not yet appeared in human experiments. In animal experiments, carnosine has been found to delay the growth of cancer cells and prevent oxidative stress caused by alcohol and chronic liver damage caused by alcohol. In mouse experiments, the neuroprotective mechanism of carnosine can prevent permanent brain ischemia.
Carnosine can enhance the Hayflick limit of human fibroblasts and the rate of telomere shortening. The maintenance of telomeres may be beneficial to the growth of certain potential cancers, so carnosine is also regarded as a protective agent. It is generally believed that typical vegetarians lack carnosine intake, but it is still unknown whether this will cause adverse effects.
 
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  • 305-84-0
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Chemical and physical properties of dextromethorphan hydrobromide



Density 1.4±0.1 g/cm3
Boiling Point 656.2±55.0 °C at 760 mmHg
Melting Point 253 °C (dec.)(lit.)
Molecular Formula C9H14N4O3
Molecular Weight 226.232
Flash Point 350.7±31.5 °C
Exact Mass 226.106583
PSA 121.10000
LogP -2.17
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.591

IMG_20200730_143638



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