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cas 59-46-1

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  • Top Quality CAS 59-46-1 Tetracaine hydrochloride with Safe Delivery and Lowest Price
    Procaine Biological Activity
    Description: Procaine is a local anesthetic drug of the amino ester group, which acts through multiple targets.Target: OthersProcaine is a local anesthetic of the ester type that has a slow onset and a short duration of action.Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM [1]. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest [2]. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale [3].
    Related Catalog:
    Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor
    Signaling Pathways >> Neuronal Signaling >> GABA Receptor
    Research Areas >> Neurological Disease
    [1]. Fan, P. and F.F. Weight, Procaine impairs the function of 5-HT3 receptor-ion channel complex in rat sensory ganglion neurons. Neuropharmacology, 1994. 33(12): p. 1573-9.

    [2]. Villar-Garea, A., et al., Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res, 2003. 63(16): p. 4984-9.

    [3]. Adamec, R.E. and C. Stark-Adamec, The effects of procaine HCl on population cellular and evoked response activity within the limbic system of the cat. Evidence for differential excitatory action of procaine in a variety of limbic circuits. Prog Neuropsychopharmacol Biol Psychiatry, 1987. 11(4): p. 345-64.
  • Pain Killer Cas 59-46-1 Procaine
    Name                        Procaine
    CAS Number            59-46-1
    Density                     1.1±0.1 g/cm3
    Molecular Formula    C13H20N2O2

  • Globally popular procaine powder cas 59-46-1 shipped via secure line
    Product Name    Procaine
    Other names    Procaine Base, 4-aminobenzoic acid 2-diethylaminoethyl ester
    CAS NO    51-05-8
    Molecular Formula    C13H20N2O2
    Molecular Weight    236.310
    Appearance    White powder

    CAS No.    59-46-1
    Other Names    Procine
    Molecular Formula    C13h20n2o2
    EINECS No    200-426-9
    Place of Origin    Anhui Province
    Purity    99%
    Form    Powder
  • Chinese top supplier procaine powder cas 59-46-1 door to door service
    Product Name    Procaine
    Other names    Procaine Base, 4-aminobenzoic acid 2-diethylaminoethyl ester
    CAS NO    51-05-8
    Molecular Formula    C13H20N2O2
    Molecular Weight    236.310
    Appearance    White powder
  • Cas 51-05-8 Procaine Hydrochloride , Cas 59-46-1 Procaine
    Name                   Pregabalin
    CAS Number       148553-50-8
    Density                1.0±0.1 g/cm3
    Boiling Point     327.8±42.0 °C at 760 mmHg
    Molecular Formula    C8H17NO2
      Name:                 Procaine hydrochloride
    CAS Number:      51-05-8
    Boiling Point:      195-196°C 17mm
    Melting Point:     155-156 °C(lit.)


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